How Ibogaine Affects Serotonin and Dopamine Receptors

How Ibogaine Affects Serotonin and Dopamine ReceptorsOne of the reasons Ibogaine is so effective at helping addicts overcome addiction is the way it works on dopamine and serotonin levels in the brain. When dependent on drugs or alcohol, these “feel good” centers in the brain can become severely altered and create extreme imbalance in the mind and one’s emotional state. Ibogaine, however, has an unprecedented positive effect on these neurotransmitters and can truly help one regain the balance they’ve lost due to addiction.

Understanding the Role of Dopamine and Serotonin in the Brain


Dopamine is what’s responsible for the elating feelings life is often filled with. When we feel extremely motivated, experience doing something we really enjoy, or fall in love, dopamine is playing a major role. When dopamine levels are off in the brain, we end up feeling depressed and lack the energy to do much of anything.

Using drugs increases the amount of dopamine in the brain. This is why doing drugs offers such a satisfying reward. With 5-10 times the normal amount of dopamine in one’s limbic brain, motivation and exhilaration are dramatically increased. The brain quickly learns that feeling this way is a direct result of doing drugs…and addiction often quickly follows.

Consistently offering the brain an increase in dopamine through the use of drugs literally creates plastic changes to the brain. It ends up desensitizing neurons and decreases the number of dopamine receptors. Cocaine and methamphetamines are directly responsible for increasing dopamine levels.


Serotonin is the other “feel good” chemical in the brain. This is one that basically helps us function and cope with daily life. It regulates our sleep and helps us to relax. Serotonin is also what’s responsible for helping us recharge and face life…whatever it may bring. It helps us feel wellbeing and is responsible for a content state of mind.

Drug use can severely affect the way serotonin is produced in the brain. Opioids and alcohol are both substances that increase serotonin production, and both quickly increase feelings of wellbeing shortly after use. Increased levels of serotonin are often what’s responsible for prompting addictive behavior, simply because of the elevated high that’s offered.

Continued drug or alcohol use can damage both dopamine and serotonin levels, leaving addicts with a psychological and physical addiction that can seem impossible to overcome. It’s for this reason that Ibogaine (and its effects on dopamine and serotonin receptors in the brain) works so well to help people looking to defeat their addictive tendencies.

How Ibogaine Affects Serotonin and Dopamine

Studies performed with Ibogaine have shown that Ibogaine increases the amount of serotonin the brain discharges, and also obstructs the brain from reabsorbing any excess serotonin that’s produced. This is responsible for increased feelings of wellbeing, without the need for drugs or alcohol to do so. Ibogaine offers a way to “feel good” again without depending on a substance to do so.

Ibogaine is also responsible for repairing dopamine receptors, while normalizing levels in the brain as well. While it doesn’t increase the amount of dopamine that’s naturally released, it does inhibit just how fast dopamine is expelled from receptors in the brain. What this means is that with Ibogaine, dopamine receptors fire with more frequency. Ultimately, this decreases the need for drugs to offer the increased feelings of elation that dopamine produces.

It’s thought that the long-term effects Ibogaine offers to the brain in concern to serotonin and dopamine levels, is because Ibogaine essentially “resets” these very important chemicals back to their pre-addicted state. Ibogaine treatment has shown to treat all addictions successfully, but is of special interest to those who have succumb to severe opioid addiction.

Ibogaine Treats Various Addictions that Affect Dopamine and Serotonin Levels in the Mind

As one of the most difficult addictions to treat, opioid dependency has become an epidemic in recent years…and is one many people are losing their lives to. Because Ibogaine shows such unprecedented results in readjusting the chemistry of the brain that has been damaged due to heavy addiction, it makes an excellent choice for those lost in the battle to heroin or opioid addiction (where serotonin is undoubtedly impaired). With brain chemistry reset back to a pre-addicted state, it’s much easier to do the rest of the work necessary to overcome the cycle of addiction for good.

Because of its ability to work so closely with the damage that has been done in the mind, Ibogaine is also excellent for the repercussions of damaged dopamine receptors from drugs like cocaine and meth. With dopamine levels restored, readjusting to life without drugs that increase dopamine becomes something that can actually be tolerated by the addict.

Ibogaine works in the brain like no other addiction treatment ever has. The importance of positively altering dopamine and serotonin levels without any further dependency issues (Ibogaine is non-habit forming) is one that should not go unnoticed by those seeking to overcome addiction for good. Excess drug and alcohol abuse basically hijack the brain and make feeling “normal” emotions and feelings almost impossible to attain.

Ibogaine offers relief from this drug-induced takeover of the brain’s natural chemical release. This relief is helping countless people overcome addiction and take back control of their lives, free from the need to alter any of the natural occurring chemicals in the mind.